The molecular mechanism of how femoroacetabular impingement (FAI) morphology leads to hip osteoarthritis (OA) is yet to be determined. Expression and location of inflammation-related molecules during early- and late-stage FAI have not been previously described. Moreover, characterization of intraarticular inflammation away from cam deformity as well as the nature of the adjacent synovial tissue has also not been extensively characterized.

In conclusion, hip cartilage exhibits an osteoarthritic phenotype in patients with early FAI similar to what was observed in hip OA secondary to FAI. Severe synovitis was only evident in late-stage disease.

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Five articles from the August 2020 issue summarized in five minutes, with the addition of a brief editorial commentary. The 5-in-5 feature is designed to give readers an overview of articles that may pique their interest and encourage more detailed reading. It may also be used by busy readers who would prefer a brief audio summary in order to select the articles they want to read in full.

The featured articles for this month are, "Dyslipidemia With Perioperative Statin Usage Is Not Associated With Poorer 24-Month Functional Outcomes After Arthroscopic Rotator Cuff Surgery", "Posterior Rotational and Translational Stability in Acromioclavicular Ligament Complex (ACLC) Reconstruction: A Comparative Biomechanical Analysis in Cadaver Specimens", "An In-Depth Analysis of Graft Rupture and Contralateral ACL Rupture Rates After Pediatric ACL Reconstruction", "Concussion Symptom Cut-offs for Identification and Prognosis of Sports related Concussion: The Role of Time Since Injury", and "Long-term Outcomes and Survivorship of Fresh-Frozen Meniscal Allograft Transplant With Soft Tissue Fixation: Minimum 10-Year Follow-up Study".

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